Culture Collections

Oesophageal Cell Lines

Adobestock 50962164A series of (o)esophageal adenocarcinoma (EAC) cell lines are available in the ECACC General Collection catalogue. The majority of these cell lines have been studied by Boonstra et al., 2010, who in a world-wide effort sought to verify the authenticity of all available EAC cell lines by comparing the cell lines to the original primary tumour tissue from the donors.

Boonstra et al. discovered that cell lines SEG-1, BIC-1, and SK-GT-5 are not EAC cell lines but large cell lung cancer cell line H460, colorectal adenocarcinoma cell line SW620, and gastric fundus carcinoma cell line SK-GT-2, respectively. However, they confirmed that cell lines FLO-1, KYAE-1, SK-GT-4, OE19, OE33, OACP4C, OACM5.1, ESO26, and ESO51 are derived from human EACs. All nine of these verified EAC cell lines, together with their genotyping information, have been deposited with ECACC.

Reference: Boonstra et al., (2010) Verification and Unmasking of Widely Used Human Esophageal Adenocarcinoma Cell Lines. J Natl Cancer Inst. Feb 24;102(4):271-4. PMCIM:PMC2902814

 

The list below shows the oesophageal cell lines available from the ECACC General Cell Collection.

In addition, you can also search the collection.

 

ECACC General Cell Collection
15 items found, displaying all items.
Catalogue No. Cell Line Name Keywords
11012009 ESO26 Adenocarcinoma of the gastroesophageal junction
11012010 ESO51 Distal oesophageal adenocarcinoma,
11012001 FLO-1 Distal oesophageal adenocarcinoma
11012002 KYAE-1 Distal oesophageal adenocarcinoma,
94072021 KYSE-270 Human oesophageal squamous cell carcinoma
94072011 KYSE-30 Human Asian squamous cell carcinoma
94072023 KYSE-410 Human oesophageal squamous cell carcinoma
94072012 KYSE-70 Human oesophageal squamous cell carcinoma
11012006 OACM5.1 C Barretts adenocarcinoma, adenocarcinoma of distal oesophagus
96071721 OE19 Human Caucasian oesophageal carcinoma
96062201 OE21 Human Caucasian oesophageal squamous cell carcinoma
96070808 OE33 Human Caucasian oesophageal carcinoma
11012008 SK-GT-2 Adenocarcinoma of the Gastric fundus, poorly differentiated
11012007 SK-GT-4 Oesophagus adenocarcinoma, well-differentiated
11012005 OACP4 C Gastric cardia adenocarcinoma,


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